Abstract: In the context of land-sea integration for territorial spaces, scientific assessment of the existing ecological environment of coastal zone to reduce the landscape ecological risks arising from land use changes and to enhance the capacity of ecosystem service provision is an important direction for the ecological environment management of coastal zone. This paper addresses the core research question of ‘how to scientifically support the ecological safety pattern for coastal zone protection and restoration by exploring the spatial correlation between ecosystem service value and landscape ecological risk’. Taking Shanghai coastal zone as an example, this paper quantitatively evaluates the landscape ecological risk index (LERI) and ecosystem service value (ESV) based on the evaluation unit of 150 m×150 m and reveals the spatial correlation between LERI and ESV used bivariate spatial autocorrelation analysis method. Ecological protection and restoration zoning is then carried out and optimization strategies are put forward. Results show that the ‘high ESV-high LERI zone’ has the advantage of resource endowment, but is seriously affected by harbour and wharf construction activities as well as marine natural disasters. The ‘low ESV-low LERI zone’ carries a small amount of production activities, and is affected by the neighbouring landscapes and ecological high-risk areas, so the ecological risk may increase. The ‘low ESV-high LERI zone’ is intensive in human production and living activities, with a high degree of modification of the original natural environment, and a large degree of impact on regional ecological risk. The ‘high ESV-low LERI zone’ has a developed tourism industry and frequent activities of tourists and residents, but the ecological restoration projects have been completed or are underway around the area, and the ecological environment is relatively good. Based on the above results, the coastal zone of Shanghai is divided into five zones for ecological protection and restoration: Thus, ecological fragile zone to protect, ecological conservation zone to prevent risk, ecological risk zone to restore, ecological potential zone to develop and ecological transition zone, and the corresponding restoration measures are proposed, which will provide references to the refined zoning and management for ecological protection and restoration in the coastal zone in mega-cities.